الفهرس 
SPINAL ANESTHESIA
Data Management (Statistical methods)Only 14 pages are availabe for public view
 |  | from | 123 |  |  |
| | | from | 123 | | |
Abstract
Background: Spinal anesthesia has a clear tendency to be used more often than epidural or peripheral nerve blocks. It is safe, easy to perform, effective, has a low failure rate, has no systemic local anesthetic toxicity, is inexpensive and has a high rate of patient satisfaction.
Aims: The aim of this study is to evaluate the analgesic, hemodynamic effects & side effects of pethidine as a sole intrathecal agent in spinal anesthesia in lower extremity surgeries (intra- and post-operatively) and compare this with the standard heavy bupivacaine alone or heavy bupivacaine plus small dose pethidine.
Methodology: This prospective, randomized (via sealed envelope), double blind study was carried out on sixty six adult patients, presenting to Ain Shams University Hospitals (from August 2014 till February 2016) for elective lower limb surgery after approval of the research ethics committee of Ain Shams University and obtaining an informed consent from each patient.
Results: Patients were randomly allocated into three equal groups (22 patients each) A, B and C. group A: Patients in this group received an intrathecal injection of preservative free pethidine(5%) 1mg/kg with dextrose 10% to reach the desired volume (3-3.5 ml). group B: Patients in this group received an intrathecal injection of pethidine 25 mg (0.5 ml) plus hyperbaric bupivacaine (0.5 % ) (2.5 – 3 ml). group C: Patients in this group received intrathecal injection of hyperbaric bupivacaine (0.5 %) (3 – 3.5 ml) as needed
Conclusion: As a conclusion, this study has supported the findings of other’s previous work that intrathecal pethidine prolongs the postoperative analgesia as evidenced by a significantly longer time to first rescue analgesia, lower VAS scores and decreased total amount of rescue analgesia needed, with minimal acceptable side effects.
Keywords: Intrathecal Heavy Bupivacaine, Pethidine, Spinal Anesthesia, Intraoperative Anesthesia, Postoperative Analgesia, Lower Limb Surgery