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Abstract Wide cleft palates and relatively wide cases with deficient palatal tissues are significant contributors to postoperative palatal fistula. Trails to optimize healing in such cases were carried out. Use of absorbable membranes was carried out to act as a scaffold attracting cellular action and revascularization. In our study we introduced a totally autogenous membrane with constant and sustained release of necessary growth factors. Platelet Rich Fibrin had been widely assessed in the last decade. Its positive effect on soft tissue healing had been extensively reported especially in plastic surgery. It had proved maximum efficiency in refractory chronic wounds, like burns and infected wounds. These results encouraged its use in oral and maxillofacial surgery. In our study, although platelet rich fibrin resulted in complication free palatal reconstruction, the control group did as well. This signifies the importance of the surgical technique and the surgeon’s experience. Platelet rich fibrin is cheap, easily prepared, easily handled and well tested autogenous membrane. If it used in association with strict surgical standard, its results will be optimal. |