الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Vitamin D is not only essential for maintaining good bone health but it also plays a role throughout the human body systems that is supported by presence of vitamin D receptors in most tissues including pancreatic tissue and cardiovascular system . Vitamin D deficiency is highly prevalent worldwide and certain groups as elderly persons , women and institutionalized persons are particularly prone to severe deficiency, It is hypothesized that hypovitaminosis D is more prevalent in elderly diabetic female patient and associated with higher fasting blood sugar (FBS) and cardiovascular risk including higher body mass index (BMI), blood pressure and lower fasting insulin level due to possible associated impaired B cell function. Objective: To identify the prevalence of hypovitaminosis D and its relation to cardiovascular risk among elderly diabetic female patients. Method: A cross sectional study conducted from the first of October 2014 to the end of March, 2016, where 163 elderly diabetic females who attended inpatient departments of Ain shams university hospital at that time were included. They underwent Careful history taking , body mass index calculation , blood pressure measurement , serum 25(OH) D measurement and assessment of insulin secretion including fasting serum C-peptide and c peptide index measurement in addition to assessment of glycemic control by fasting blood sugar estimation and assessment of insulin resistance by HOMA 2 . Results: the prevalence of vitamin D deficiency among elderly diabetic female patients is 71.2% and it is significantly associated with lower fasting C peptide level and c peptide index . Key words : hypovitaminosis D , elderly female , c peptide index, HOMA 2 |