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Abstract Voice outcome after injection of Hyaluronic acid in cases of unilateral vocal fold paralysis Abu El-Ella M (1), Badr El-Deen B(2), Hegazi M(1) , SarwatS (1), Boshnaq M (1) (1) Unit of Phoniatrics, Faculty of Medicine, Ain Shams University (2) E.N.T. Department, Faculty of Medicine, Ain Shams University Introduction Voice disorders resulting from glottic insufficiency are a significant clinical problem in everyday phoniatric practice. When one side is paralyzed it doesn’t move toward the center to meet the other side. This leaves a gap in the center which causes a whispery voice. Secondary to the loss of glottic closure, patients can experience dysphonia, dysphagia, and potentially respiratory compromise. . Injection laryngoplasty is considered one of the methodsfor treatment. The aim of this study is to evaluate voice outcome in patients with unilateral vocal fold paralysis injected with Hyaluronic acid. Methods Patients with unilateral vocal fold paralysis ofsymptoms less than one year with a glottal gap less than 3 mmwere included in the study. All patients were subjected to office-based intrafolder Hyaluronic acid injection in the affected vocal fold. Size of the gap, acoustic study’s parameters were measured pre and post injection. Subjective voice assessment using 0-5 score (0 means no dysphonia and 5 means severe dysphonia) was also conducted pre and post injection. Length of follow up was 6 months. Results The study included 30 patients, 16 females and 14 males. Age ranged between 17 and 61.Pre injection voice assessment was between 3 and 5. Post injection 24 patients scored 0, and 6 patients scored 1. Injection achieved complete glottic closure during phonation, except 4 patients who had minimal phonatory waste. Conclusion Injection of Hyaluronic acid under direct visual control for medialization of the paralyzed vocal fold facilitates almost complete glottic closure. It is a safe, quick and effective technique which can reduce the need for permanent laryngoplasty in patients with less than 3 mm glottal gap. Key words Vocal fold paralysis, vocal fold, vocal fold injection, vocal fold paralysis, Hyaluronic acid |