الفهرس 
Neonatal anemiaOnly 14 pages are availabe for public view
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Abstract
Anemia of prematurity is commonly observed in infants born at less than 34 weeks gestation as an exaggerated form of the normal physiologic anemia of infancy, it is normocytic, normochromic anemia characterized by reduced bone marrow erythropoiesis. Anemia of prematurity is multifactorial due to inadequate placentofetal transfusion , blood losses, RBCs mass is decreased at birth RBCs survival is decreased compared with the term infants ,and the rapid rate of growth . AOP may be associated with clinical signs of tissue hypoxia, such as tachycardia, tachypnea, difficult feeding, and metabolic acidosis and may be heart failure. The primary pathological abnormality implicated in the development of anemia of prematurity is inadequate production of erythropoietin, whose function is the regulation of red blood cells production. Also one of the most common causes of late hypo regenerative anemia that occur in full term infants at the age of 2-3 months following acute hemolysis either due to Rh or ABO incompatibility is inadequate production of erythropoietin and bone marrow suppression following frequent blood transfusions. Recombinant human erythropoietin (r-Hu EPO) has been available for clinical use since 1985 .it was an immediate success in treating anemia of prematurity in either a therapeutic or prophylactic setting.