الفهرس 
ِِِAcknowledgementOnly 14 pages are availabe for public view
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Abstract
This study was performed on 80 pregnant women with severe preeclampsia, who met one or more of the inclusion criteria with age ranging from 20 to 35 years and gestational age ranging from 28 to 36 weeks gestation. The patients were from Womenʼs Health Hospital, Assiut University, in the Years from 2014 to 2015 and the study was done in the clinical pathology department of Assiut University. The control group comprises 20 normal pregnant women with age and gestational age of the same range as cases.
The following were done:
1- Medical history and clinical examination:
-Complete history taking and clinical examination
2- Blood sample for laboratory investigation:
Ten ml of venous blood were collected under complete aseptic conditions
3-Laboratory investigations:
1- Complete bloodand reticulocytic counts.
2-Prothrombin time (PT) and activated partial thromboplastin time (aPTT).
3-Liver function tests, kidney function tests and RBG.
4-Lupus anticoagulant tests.
5-Anti-Cardiolipin(IgG/IgM) antibodies.
6- Anti-β2GPI antibodiesIgG.
Note: The study was postponed to the cases of eclampsia to the difficulty of taking samples from this group due to convulsions and lack of material possibilities
The current study showed the following findings:
This study using DRVVT lupus anticoagulant, Anticardiolipin and Anti-beta-2-Glycoprotein I assays had found the prevalence of APA in severe pre-eclampsia women to be 6.25%, while none (0%) of the controls was positive showing that there is a relation between presence of APA and development of severe pre-eclampsia.