الفهرس | Only 14 pages are availabe for public view |
Abstract Abstract Background: Fibroids remain the commonest pelvic tumour seen in women with myomectomy being the major form of treatment in our environment. Techniques to minimize blood loss will reduce patient morbidity and the need for blood transfusions. One such technique is the use of a tourniquet during myomectomy operation. Aim of the Study: The aim of the current study is to compare between the effect of medical (pre-operative intravenous tranexamic acid) and non-medical (peri-cervical mechanical tourniquet) regarding their efficacy to decrease blood loss in trans- abdominal myomectomy. Patients and Methods: A prospective randomized controlled interventional clinical trial. The study was conducted in Ain Shams University Maternity Hospital, Cairo, Egypt in the period from August 2015 till January 2017. It was approved by the Ethical Research Committee, Obstetrics and Gynecology Department, Ain Shams University, Cairo, Egypt. It included seventy women recruited those attending the outpatient gynecology clinic, seeking treatment for symptomatic leiomyomas, in the period between August 2015 till January 2017. Results of the thesis showed that pericervical tourniquet is more effective than tranexamic acid in decreasing blood loss during myomectomy operation besides decreasing the need for blood transfusion and iron therapy. Conclusion: Tourniquet is more effective than tranexamic acid besides being a cheap method and should be used in all myomectomy operations when possible. Recommendations: Further studies should compare the addition of tranexamic acid to tourniquet in decreasing blood loss intraoperative and postoperative with using tourniquet alone. Key words: tourniquet, tranexamic acid, myomectomy, blood loss |