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Abstract Abnormal uterine bleeding (AUB) is one of the primary indications for a gyneco-logic consultation, accounting for approximately 33% of all gynecology visits, and for 69% of visits among postmenopausal women. (105) Confirming the etiology and planning appro-priate intervention is important in the clinical management of AUB because accurate diag-nosis may result in avoiding major gynecologic surgery in favor of minimally invasive hys-teroscopic management. It is generally accepted that the initial evaluation of women with AUB is performed with noninvasive transvaginal ultrasound (TVUS). (106) However, the accuracy of TVUS is limited in the diagnosis of focal endometrial lesions, and further investigation of the uterine cavity is warranted. Evaluation of the uterine cavity with sonohysterography (SH), vaginal ultrasound with the instillation of saline into the uterine cavity is more accurate than TVUS alone. Yet, diagnostic hysteroscopy (DH) has proven to be superior to either modality for the accurate evaluation of intracavitary pathology. (106) In the present study, fifty adult females in the reproductive age period (20 – 45) complaining of abnormal uterine bleeding were subjected to diagnostic hysteroscopy in the outpatient clinic. Comparison of the findings in the office hysteroscopy and a prior endo-metrial curettage was done to calculate the diagnostic accuracy of both diagnostic tools. Office hysteroscopy had a higher specificity and sensitivity than endometrial curet-tage; which led to a more superior diagnostic accuracy than D&C in the diagnosis of causes of abnormal uterine bleeding in pre-menopausal women. |