الفهرس 
Breast CancerOnly 14 pages are availabe for public view
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Abstract
Breast cancer is the most common type of cancer and is the second leading cause of cancer-related mortality in women. The cfDNA has been implicated as strong diagnostic and prognostic markers because the expression of cfDNA is usually altered in malignancies. It is believed that the sources of cfDNA in blood stream are necrotic and apoptotic cells.
The aim of the work is to quantitatively measure CFDNA concentration in patients with malignant breast cancer compared with benign breast tumors and healthy controls. Also, to investigate their potential role as a non-invasive tool for breast cancer detection.
The present study included 50 subjects. The studied subjects were divided into three groups, group I included 30 newly diagnosed breast cancer female cases, their ages ranged from 32 to 62 years, group II included 10 female patients with benign breast lesions, their ages ranged from 33 to 52 years and group III included 10 females of apparently healthy and age matched controls, their ages ranged from 39 to 60 years.