الفهرس 
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Abstract
Coronary artery bypass graft (CABG) surgery has been shown to be an effective method for treating angina pectoris and prolonging life in patients with severe coronary artery disease.
Cardiac surgery associated acute kidney injury (CSA-AKI) is a common complication after CABG surgery.
CSA AKI has been associated independently with increased mortality, morbidity.
This study explored the incidence of renal dysfunction after coronary artery bypass graft surgery and the risk factors of post-operative renal dysfunction.
This study was performed on 290 adult patients admitted to perform open heart surgery for CABG in the cardiothoracic surgical department in Sharqe Elmadina hospital, Alexandria, Egypt from 1/1/2013 to 31/12/2014 after exclusion of patients with pre- operative renal dysfunction.
Patients were divided into two groups according to the occurrence of post-operative renal dysfunction according to RIFLE criteria.
Sixty two patients (21.37%) of the 290 study patients were classified to have postoperative renal dysfunction, Stage of risk 48 patients which represent (16.5%) of the total number, stage of injury 8 patients which represents (2.75%) of the total number, stage of failure 6 patients which represents (2.06%) of the total number.
Three of six patients (50%) at the stage of failure required dialysis. They represent about (4.83%) of 62 patients with post-operative renal dysfunction and about (1%) of 290 patients of the study.
The incidence of mortality between patients with post-operative renal dysfunction (5 of 62: 8%) was higher than that of patients with normal post-operative renal function(2 of 228: 0.87%), and the incidence of mortality increase with increased severity of renal dysfunction.
After statistical analysis of the results, it was found that the risk of post-operative renal dysfunction increase with increasing age.
As regards DM there was a statistically significant difference during univariate analysis but not in multivariate analysis. And as regards HTN there was a statistically significant difference during univariate analysis but not in multivariate analysis, while as regards reduced ejection fraction there was a statistically significant difference between two groups with increased risk of renal dysfunction in case of reduced ejection fraction. Also as regards cardiopulmonary bypass time there was a statistically significant difference between two groups with increased risk of renal dysfunction with increased time during cardiopulmonary bypass. As regards post-operative bleeding there was a statistically significant difference between two groups with increased risk of renal dysfunction with increased bleeding. And As regards post-operative hemodynamic instability there was a statistically significant difference between two groups with increased risk of renal dysfunction with hemodynamic instability.