الفهرس 
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Abstract
Nephrotic syndrome is the most common primary glomerular disease among children. It causes substantial morbidity because it typically runs a relapsing course with prolonged periods of corticosteroids and other immunosuppressive medication.
Soluble urokinase plasminogen activator receptor (SuPAR) has been regarded as an inflammatory as well as a permeability factor.
The aim of this study was to evaluate serum soluble urokinase plasminogen activator receptor level in children with nephrotic syndrome and its relation to different clinical and laboratory data.
Our study was carried out on 75 children who were already diagnosed as having nephrotic syndrome, classified into 3 groups (steroid sensitive, steroid dependent and steroid resistant). Blood samples were taken to evaluate serum soluble urokinase plasminogen activator receptor, renal function tests (urea, creatinine), serum albumin, lipid profile (serum cholesterol, serum triglycerides) and CRP, Also urine sample was taken to evaluate 24 hour protein in urine.
Our study found that, SuPAR level was significantly different between the studied groups being highest in steroid resistant, then steroid dependent, then steroid sensitive and lowest in control group. Also, SuPAR had significant correlations with proteinuria and serum albumin.
In conclusion, SuPAR level assay would help to evaluate steroid response in children with nephrotic syndrome.