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العنوان
Immunohistochemical Expression of Human Beta-Defensin-2 in Verruca Vulgaris /
هيئة الاعداد
باحث / شيماء احمد وجيه شاهين
مشرف / امانى محمد عبد المنصف
مشرف / عبير عبد الحكم هديب
مشرف / صافيناز حمدى الشوربجى
الموضوع
Dermatology. Venereology.
تاريخ النشر
2017.
عدد الصفحات
104 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأمراض الجلدية
تاريخ الإجازة
18/6/2017
مكان الإجازة
جامعة طنطا - كلية الطب - Dermatology and Venereology
الفهرس
Only 14 pages are availabe for public view

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Abstract

Cutaneous warts are common dermatological conditions caused by HPV. Although it is a benign condition, it causes disfigurement, has a tendency to koebnerize, and can be transmitted to others. The majority of common warts are caused by HPV types 1, 2, 4, 27 or 57. Warts are common in children and adolescents. The prevalence of occurrence in children and adolescents is between 3-5%. Antimicrobial peptides are small cationic peptides which protect their hosts against a vast array of microorganisms. Two major families of AMPs have been characterized in mammals; defensins and cathelicidins. Defensins have direct antimicrobial and immunomodulatory properties. HBD -2 is a cysteine rich cationic 41 amino acid AMP of low molecular weight which was first discovered in 1997 in human skin. The hBD -2 that has important role in fighting bacteria, may also exert antiviral function. Tendency for remission of verrucae could be caused by antiviral proteins like defensins.