الفهرس 
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Abstract
The present study aimed at assessing the right atrial function in pulmonary hypertension patients using two-dimensional speckle tracking echocardiography as a noninvasive and quantitative method of assessment.
This study included 50 patients with pulmonary hypertension (group I) referred to the cardiology department, Benha University Hospital and were compared with 50 healthy individuals (group II) of matched age and gender.
They were assessed for baseline characteristics, admission data, electrocardiography and echocardiographic parameters.
Patients with pulmonary hypertension had greater RA volumes (maximal and minimal), greater RV areas (end systolic and end diastolic), volumes (end systolic and end diastolic) and greater estimated pulmonary artery systolic pressure(PASP) but lower RV fractional area change (FAC) and lower tricuspid annular plane excursion (TAPSE).
There was no significant statistical difference between the 2 groups regarding left ventricular ejection fraction, Left ventricular end diastolic volume (LVEDV), left ventricular end systolic volume (LVESV).
Right atrial and ventricular global longitudinal strain (RAGLS% and RVGLS %) were significantly reduced in patients pulmonary hypertension.
Peak global right atrial longitudinal strain (RALS) showed a significant negative correlation with RA volumes (maximal and minimal), and negative correlation with tricuspid annular plane excursion (TAPSE). The correlation between peak global RALS and WHO classification was negative but very weak .Also, the correlation between peak global RALS and 6 minute walk test was very weak but positive
Peak global right ventricular longitudinal strain (RVLS) showed a significant negative correlation with tricuspid annular plane excursion (TAPSE), and negative correlation with RV fractional area change (FAC). The correlation between peak global RVLS and 6 minute walk test was negative but very weak .Also, the correlation between peak global RALS and WHO classification was very weak but positive
The receiver-operator characteristic (ROC) curve was used to test diagnostic value of right atrial global longitudinal strain to detect RV dysfunction (defined as FAC < 35%). The value of systolic RA strain ≤ 26.5 was shown to have the best diagnostic accuracy (sensitivity = 85.70%; specificity = 90.90%) in predicting the presence of RV dysfunction, with an AUC of 0.957.
The receiver-operator characteristic (ROC) curve was used to test diagnostic value of right ventricular global longitudinal strain to detect RV dysfunction (defined as FAC < 35%). The value of systolic RV strain ≤ -20.5 was shown to have the best diagnostic accuracy (sensitivity = 100%; specificity = 98.60%) in predicting the presence of RV dysfunction, with an AUC of 0.986.
Pulmonary hypertension patients with enlarged right atrial size had greater RA volumes (maximal and minimal), greater RV areas (end systolic and end diastolic) and volumes (end systolic and end diastolic) , greater estimated pulmonary artery systolic pressure (PASP) but lower RV fractional area change (FAC) ,lower tricuspid annular plane excursion (TAPSE) and lower right atrial and right ventricular global longitudinal stain (RAGLS% and RVGLS%).