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العنوان
Inhaled beta-2 agonist versus epinephrine for treatment of transient tachypnea of newborn :
المؤلف
Soliman, Nahed Soliman Ahmed.
هيئة الاعداد
باحث / ناهد سليمان أحمد سليمان
مشرف / شادية السلاب
مشرف / عبدالعزيز عطاالله شعبان
مناقش / مصطفى العيوطى
مناقش / عبدالرحمن محمد المشد
الموضوع
Drug Therapy. Asthma - Drug therapy.
تاريخ النشر
2017.
عدد الصفحات
78 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
01/05/2018
مكان الإجازة
جامعة المنصورة - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

from 110

from 110

Abstract

Postnatal respiratory complications among term infants are common. The most commonly reported cause of neonatal respiratory distress is transient tachypnea of the newborn. Transient tachypnea of newborn (TTN) is a self-limiting disorder that requires minimal intervention, and resolves over a 24-to 72-h period without significant morbidity. However, it may cause severe morbidity (i.e. hypoxia, respiratory distress, and pulmonary air leak), unnecessary antibiotic use, and parental anxiety. The currently accepted mechanism of trans-epithelial movement of lung fluid at the time of birth is by passive movement of Na through ENaC, which is closed during fetal life but activated by adrenergic stimulation near birth. TTN results from delayed desorption of fluid from the lungs of newborn With salbutamol inhalation, there were lower respiratory rate, lower TTN Downes’ score, lower level of respiratory support, lower duration of respiratory support and lower duration of hospitalization than control With epinephrine inhalation, there were lower respiratory rate, lower TTN Downes’ score, lower levels respiratory support, lower duration of respiratory support and lower duration of hospitalization than control. Insignificant difference was found between salbutamol and epinephrine groups. As regard adverse effects of the intervention drugs: we did not found significant adverse effect as hypokalemia, hyperglycemia or arrhythmia.