الفهرس | Only 14 pages are availabe for public view |
Abstract Postnatal respiratory complications among term infants are common. The most commonly reported cause of neonatal respiratory distress is transient tachypnea of the newborn. Transient tachypnea of newborn (TTN) is a self-limiting disorder that requires minimal intervention, and resolves over a 24-to 72-h period without significant morbidity. However, it may cause severe morbidity (i.e. hypoxia, respiratory distress, and pulmonary air leak), unnecessary antibiotic use, and parental anxiety. The currently accepted mechanism of trans-epithelial movement of lung fluid at the time of birth is by passive movement of Na through ENaC, which is closed during fetal life but activated by adrenergic stimulation near birth. TTN results from delayed desorption of fluid from the lungs of newborn With salbutamol inhalation, there were lower respiratory rate, lower TTN Downes’ score, lower level of respiratory support, lower duration of respiratory support and lower duration of hospitalization than control With epinephrine inhalation, there were lower respiratory rate, lower TTN Downes’ score, lower levels respiratory support, lower duration of respiratory support and lower duration of hospitalization than control. Insignificant difference was found between salbutamol and epinephrine groups. As regard adverse effects of the intervention drugs: we did not found significant adverse effect as hypokalemia, hyperglycemia or arrhythmia. |