الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Warts are benign proliferation of skin and mucosa that result from infection with human papilloma virus (HPV) which are doublestranded deoxyribonucleic acid (DNA) viruses that replicate inside the nucleus. Wart occurs at any age but it is unusual in infancy and early childhood. The incidence increases in the school years to reach a peak between the age 12 and 16 years, then declines sharply to the age of 20 years, and more gradually thereafter. Infection with HPV may be clinical, subclinical, or latent.
A range of types of wart have been identified, varying in shape and site affected, as regards the type of human papillomavirus involved Common wart (Verruca vulgaris), Plane wart (Flat wart or Verruca plana), Plantar wart (verruca, Verruca plantaris), Filiform or digitate wart, Anogenital wart a wart that occurs on the genitalia. And Periungual wart.
Plane warts are caused by HPV type 3 and 10, occur mostly in children and young adults. The face, back of the hands, and the shins are the site of predilection. Lesion usually presented as 2 to 4 mm flat topped papules that are slightly erythematous or brown on pale skin and hypo pigmented on darker skin. Useful finding is the tendency of plane warts to koebnerize forming linear, slightly raised papular lesions. Lesion may resolve spontaneously within one month, particularly when inflamed or it may stay for long time to resolve.
Many modalities of treatment were used to treat plane warts, but none is uniformly effective, these includes topical Salicylic acid, Imiquimod, 5Flourouracil, Isotretinoin gel 0. 05%, topical zinc sulfate solution, oral zinc sulfate, cimetidine, Bacillus CalmetteGuérin (BCG) vaccination, curettage/ electrodessication, cryotherapy and potassium hydroxide.
Potassium hydroxide (KOH) is an incredibly strong metallic base. In medical practice, it is used in the diagnosis of fungal infection, whiff test for diagnosis of bacterial vaginosis, treatment of male genital wart, and treatment of molluscum contagiosum in children.
An opened therapeutic study where a total number of 100 patients with plane warts were enrolled in this study, they were selected from Mansoura University Hospital and Central Dekirnes Hospital, Inclusion criteria included patients with no specific age, both males and females, having plane warts whatever the site of them, exclusion criteria included patients who are receiving steroid or other immune suppressant drugs, those with history of chronic illnesses or immune suppressed conditions, pregnant and nursing woman, those who receive any modality of treatment for their warts at least for the previous two months, and patients refusing this therapeutic trial.
The nature of the disease, course, prognosis, and full information related to the therapy including the possible side effects, action, and way of application were explained to the patients. Formal consent was taken from each patient prior to their inclusion in this study.