الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
MRI is an ideal non-invasive technique and superior to other imaging modalities in the evaluation of pelvic abnormalities. The anatomical relation of the visceral organs, the differential zonal anatomy of the corpus uteri and the cyclical endometrial changes during the menstrual cycle are well depicted with MRI. MRI tells us the exact volume, shape, and direction of the primary lesion, local extent of the disease, and nodal status accurately, which helps the clinician in treatment planning. Tumor behavior to chemoradiation is also better evaluated with MRI. Although the final diagnosis of the endometrial carcinoma is based on the histological examination, it is desirable to preoperatively decide whether surgery is required, and which type of surgery is appropriate. Thus, it can help avoiding unnecessary surgery especially in postmenopausal women. TVUS is the first imaging modality that can be used for detection of uterine mass lesion. However, lesion characterization is done with the help of MRI. Conventional MRI provides soft tissue characterization based on different signal intensities and contrast uptake in post contrast images.
The purpose of this study is to evaluate the impact of Magnetic resonance imaging in preoperative staging of endometrial carcinoma, with special focus on: Evaluation of sensitivity and specificity of Magnetic resonance imaging staging, with cyto-histological diagnosis taken as the reference.Conclusion: On combined evaluation of high b value DWI and conventional MRI data, myometrial infiltration was correctly assessed in 17 (85%) patients, was underestimated in 1 (5%) patients, and was overestimated in 2 (10%) patients. On evaluating the T2WI with the post contrast T1 W images, correct diagnosis of the depth of myometrial invasion was done in 16 (80%) of cases. Misinterpretation was done in 4 cases (20%). The high b value DWI showed higher sensitivity in evaluating the depth of myometrial invasion compared to the post contrast images (92% and 86% respectively). The specificity was equal (82%). Correlation of the ADC values with the different histological grades was done. The mean ADC values were 0.78 ± 0.09 _10_3 mm2/s for grade 1 (G1), 0.77± 0.12 _ 10_3 mm2/s for grade 2 (G2), and 0.75 ± 0.1 _ 10 _3 mm2/s for grade 3 (G3), respectively, showing no significant correlation between ADC values and tumor grade (p= 0.67)MR imaging with its superior soft-tissue resolution is the single best modality for the preoperative staging of endometrial carcinoma.