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العنوان
Comparison between Effect of Enoxaparin and Clopidogrel on Improving Pregnancy Rate in ICSI:
”A Randomized controlled trial”/
المؤلف
Mohammed,Mai Essam ElDin
هيئة الاعداد
باحث / مي عصام الدين محمد
مشرف / محمد أشرف محمد فاروق قرطام
مشرف / مصطفى إبراهيم إبراهيم عبدالمنعم
مشرف / عمرو أحمد محمود رياض
تاريخ النشر
2017
عدد الصفحات
198.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة عين شمس - كلية الطب - Obstetrics and Gynecology
الفهرس
Only 14 pages are availabe for public view

from 198

from 198

Abstract

Introduction: The success of ART varies from 30% to 50%; hence various adjuncts have been employed during assisted reproduction to increase the likelihood of pregnancy and live birth.
Objective: The oobjective of this study is to assess the efficacy of clopidogrel in comparison to enoxaparin and no treatment in improving clinical pregnancy outcome in women underlying ICSI.
Subjects and Methods: This randomized controlled trial included 150 ICSI patients divided into three groups each consisting of 50 patients: group A: ICSI Patients receiving Enoxparin, group B:ICSI Patients receiving Clopidogrel, and group C (control group): ICSI Patients do not receive neither Enoxparin nor Clopidogrel .They received the drugs on day of trigger and were assessed for occurrence of clinical pregnancy by ultrasound. Results: After adjustment for the age, BMI, and type and cause of infertility, there was no statistically significant relation between enoxaparin or clopidogrel and occurrence of clinical pregnancy (p-values, .599 and .832, respectively). A male cause for infertility was an independent predictor for the failure to achieve chemical pregnancy (odds ratio, 0.192; 95% CI, 0.086 to 0.428; p-value, <.001) Conclusions: there is no statistically significant relation between enoxaparin or clopidogrel and occurrence of clinical pregnancy. So it is worthy to perform ICSI without use of either enoxaparin or clopidogrel as adjuncts.