الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 91 |  |  |
| | | from | 91 | | |
Abstract
Urinary tract infection (UTI) is one of the most common diseases encountered in clinical practice today.
Urinary tract infection is not only common but the range of clinical effects varies from asymptomatic bacteriuria to acute pyelonephritis.
Nearly 50% of all women develop symptoms of urinary tract infection at some stage during their life.
The urinary tract undergoes profound physiological and anatomical changes during pregnancy facilitating the development of bacteriuria both symptomatic and asymptomatic in women.
Symptomatic bacteriuria is an iceberg of total bacteriuria. Pregnancy is a provocation for the asymptomatic to become
symptomatic.
About 10% 0f those with asymptomatic bacteriuria develop symptomatic bacteriuria during pregnancy. Symptomatic bacteriuria poses no problems because it is easy in diagnosis and treatment due to its overt symptoms but asymptomatic bacteriuria is difficult to diagnose and it is more common in pregnant women than non-pregnant women.
Asymptomatic bacteriuria is especially important in pregnancy because 30-40% of untreated pregnant women with asymptomatic bacteriuria develop acute pyelonephritis at the late pregnancy. Also there is evidence that when there is no symptom, untreated bacteriuria in pregnancy may lead to less favorable pregnancy outcomes and complications like preterm delivery, low birth weight, pre-eclampsia and anemia of pregnancy. Prematurity is one of the leading causes of perinatal mortality. Uterine contractions may be induced by cytokines
and prostaglandins, which are released by microorganisms.
Very little is known about possible biological mechanisms of preterm labor in women with asymptomatic bacteriuria, but a few studies on this subject have been published. However,
despite the fact that the synthesis of both estrogen and progesterone is known to increase throughout pregnancy, the incidence of bacteriuria does not increase as the pregnancy approaches term.
In conclusion, the present study showed that the incidence of ASB in preterm labor at Beni Suief General Hospital is 3%.
The most common pathogen is Klebsiella, the most sensitive antimicrobial are cefoperazone, gentamycin, nalidixic acid, norfloxacin and ciprofloxacin.
Anemia is associated with higher incidence of ASB .patients with past history of UTI is associated with higher incidence of ASB.
Routine ANC is important in prevention of ASB, urine culture is recommended during the first antenatal visit, urine culture is also recommended in each trimester.