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العنوان
Cyclophosphamide in Biologic Naïve Rheumatoid Arthritis patients Resistent to Traditional DMARDs/
المؤلف
Abd Ellah,Asmaa Mortada
هيئة الاعداد
باحث / أسماء مرتضى عبد اللاه
مشرف / هويدا السيد منصور
مشرف / نوران أسامة أحمد العزيزى
مشرف / مها أحمد السروى
تاريخ النشر
2017
عدد الصفحات
158.P:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة عين شمس - كلية الطب - Internal Medicine
الفهرس
Only 14 pages are availabe for public view

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from 156

Abstract

There was no significant statistical correlation between patients with positive and negative RF and different disease activity markers except for Hb level showing significant increase in patients with positive RF post-treatment with CYC (P-value=0.042), there was also no significant statistical correlation between patients with positive and negative ACCP and different disease activity markers except for Plt level showing significant decrease in patients with positive ACCP post-treatment with CYC (P-value=0.034).
Higher CRP at baseline in RA patients indicates poor response to treatment and higher VAS at study endpoint.
IV pulse CYC and methylprednisolone (MP) are of a significant benefits in induction of remission in resistant aggressive RA patients who failed to respond to traditional DMARDs.