الفهرس 
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Abstract
The present study was conducted to identify and quantify the phenolic profile of parsley seeds and green parts methanolic extracts, to investigate the essential oil composition extracted from parsley seeds, to purify bioactive components from green parts ethyl acetate fraction, studied hypouricemic and hypolipidemic effects on rats and to investigate the antimicrobial activity of this mentioned preparations. Results revealed that parsley seeds methanolic extract contained higher amount of polyphenols than leaves methanolic extract. Rosmarinic acid was the most detected compound in parsley seed methanolic extract (38777 μg/g) meanwhile in green parts methanolic extract (as 21468 μg/g). Apiol was the main constituent of the essential oil of parsley seeds (45.21 %). Ethyl acetate fraction of the green parts was employed to TLC chromatographic analysis. The component of the main band was purified with preparative thick layer chromatogram PTLC .The obtained data from NMR spectrum for the purified component showed the presence of Kaempferol 3-arabinofuranoside. Biological experimental for hypouricemic effect revealed that animals were effected by the treatment of garamicin. All blood constituent were increased, while sodium, potassium and total protein were decreased. Treatment with parsley methanolic extract or butanol green parts and ethyl acetate seeds fractions improved all blood constituents. For hyperlipidemic animals: experimental animal were fed with corn meal in addition to 15% ghee to produce hyperlipidemia. When rats treated with methanolic extracts of parsley green parts or seeds with 500 and 250 mg/kg, respectively TG, TC, HDL-c, LDL-c, VLDL – c, AST and ALT nearly reactael to the negative control group. Seeds and green parts methanolic extracts were evaluated as antimicrobial agent along with Kaempferol 3-arabinofuranoside in a comparative study with seeds essential oil. Aromatic oil of Petroselinum crispum was the most effective against Escherichia coli, Staphylococcus aureus , Salmonella typhi. Fusarium oxysporum, and Alternaria alternate being with inhibition zones 25.6 , 23.8 , 30.0 30.22 and 25.64 mm, respectively. Kaempferol 3-arabinofuranoside demonstrated moderated antibacterial activity against the examined microbes.