الفهرس 
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Abstract
Perinatal hypoxic ischemic cerebral injury remains an important issue
partly because it is the most clearly recognized cause of cerebral palsy.
Most cases of hypoxic ischemic encephalopathy result from injury in the
perinatal period secondary to intrauterine asphyxia, with disturbance of
gas exchange across the placenta.
The aim of this study was to assess the patients of hypoxic ischemic
encephalopathy and to establish a simple and quick method that could be used to predict occurrence of hypoxic ischemic encephalopathy as early as possible to improve efficiency of short term prognosis of asphyxia in neonates by assessment of level of both nucleated red blood cells and lactate in cord blood in the first few hours after delivery.
Our study included 30 full term neonates diagnosed as hypoxic
ischemic encephalopathy fulfilled the criteria of AAP, compared with 30
age and sex matched apparently healthy term neonates as a control group with no obstetrical problems, delivered either vaginaly or by cesarean section. Some risk factors associated with HIE were assessed among our
patients and we found that diabetic mellitus and anemia were the most
common maternal risk factors while preeclampsia and placenta previa were the most obstetric factors in cases with HIE.
Umblical cord nucleated red blood cells were able to predict hypoxia and to assess the grade of hypoxia while cord lactate had better ability to predict hypoxia but can’t assess the grade of hypoxia. Both Nucleated red blood cells and lactate were able to predict hypoxic ischemic encephalopathy early after labor as they had better sensitivity and specificity together than each one alone.