الفهرس 
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Abstract
A total of 1000 clinical samples including blood (n=70), trachea secretion (n=146), burn (n=129), sputum (n=287), stool (n=78), urine (n=165) and wound (n=125) were collected from ICU, Burns department, Chest Disease departments and department of Clinical Pathology of Tanta university hospital during the period from April 2014 to October 2014. All samples were cultured on MacConkey agar where 587 (58.7%) Gram negative bacteria were isolated. It was found that 104 out of 587 (17.7%) isolates were imipenem resistant (IMPR) using Muller Hinton agar plates containing the break point concentration 4 μg/ml of imipenem.