الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 86 |  |  |
| | | from | 86 | | |
Abstract
The present study was conducted to investigate the immune-modulatory effects of norfloxacin on cellular and humoral immune response of rabbits either non-vaccinated or vaccinated with rabbit hemorrhagic disease virus vaccine. In this study, twenty (20) NewZealand white rabbits of 3-4 month old and weighting about 2-2.5 Kg were used.
They were classified into 4 groups as the following:
1-The first group (G1) was left as a control, non -vaccinated non –treated
2-The second group (G2) vaccinated non-treated group was subcutaneously injected with inactivated rabbit hemorrhagic disease virus vaccine at dose of 0.5 ml per rabbit.
3-Third group (G3) vaccinated –treated group was orally administrated with norfloxacin by stomach tube at dose 28mg per rabbit daily for 5 successive days then vaccinated at 5th day of treatment by inactivated rabbit hemorrhagic disease virus vaccine at dose of 0.5 ml per rabbit.
4-Fourth group (G4) non-vaccinated treated group was orally administrated with norfloxacin by stomach tube at dose 28mg daily for 5 successive days.
Sampling:
Two blood samples were collected from the ear vein of each rabbit (5rabbits/group) at zero time (before vaccination and drug administration) and subsequently collected at (1st, 2nd, 3rd) day and (1st, 2nd, 3rd) week post vaccination and /or drug administration for studying both cellular and humoral immune response.