الفهرس 
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Abstract
Systemic lupus erythematosus is a chronic autoimmune disorder of the connective tissue. The pathogenesis of SLE still unclear, however abnormal immune tolerance and over activation of T and B lymphocytes are considered to be the main causes. NKT lymphocytes are one subset of T lymphocytes that possess features of both natural killer (NK) cells (CD56+ and CD161+ expression) and conventional T lymphocytes (CD3+ expression). They regulate the killing function of these cells by interacting with MHC class I molecules, which are expressed on all cell types. This suggests that NKT cells play a regulatory function suppressing autoimmunity.