الفهرس | Only 14 pages are availabe for public view |
Abstract Infertility is one of the major health problems in life and approximately about 30% of this problems due to male factors, that play an important role in impair male reproductive capacity causing transient or permanent infertility. However, intake of natural antioxidants with vitamins E can protect sperm DNA from oxidative stress. The present study was designed to evaluate the protective effect of vitamin E and ginseng on adverse effects of cyclophosphamide on male fertility. Experimental design: After one week of acclimatizaion, sixty adult male albino rats were weighed and randomly allocated into 6 equal groups, each of 10 animals. group 1: (Control) rats were received 0.5 ml distalled water for 60 days. group 2: (PG): rats were given panex ginseng (PG) 200 mg / kg/b.wt. once daily for 60 successive days orally. group 3: (Vit E): rats were given vitamin E 100 mg/kg b.wt. once daily for 60 successive days orally as standard antioxidant. group 4: (CP): rats were given Cyclophosphamid (CP) 100 mg/kg b.wt (I.P) twice weekly for 60 successive day group 5: (PG +CP): rats were given panex ginseng (PG) 200 mg/ kg b.wt once daily two hours before CP administration (100 mg/kg b.wt.( I.P) twice weekly) for 60 successive days. |