الفهرس | Only 14 pages are availabe for public view |
Abstract In industrialized countries, group B streptococci(Streptococcus agalactiae,GBS) have been a leading cause of morbidity and mortality among newborns for more than 30 years. Resulting in pneumonia, sepsis and meningitis. Pregnant women may also manifest disease association with GBS including urinary tract infection(UTI and/or serious diseases such as chorioamnionitis, endometritis and bacteremia during preg-nancy,delivery or postpartum period.Furthermore, maternal infection may cause preterm delivery, low birth-weight infants or stillbirths. GBS colonization is asymptomatic and occurs in a transient, chronic or intermittent manner and the colonization period is variable; therefore, detecting GBS in vaginal tract at certain times of pregnancy could indicate the existence of this bacterium at delivery. During the past decade,major initiatives have been proposed to prevent GBS disease. The main goal of preventative strategies is to reduce or eliminate transmission of GBS to the infant by giving antibiotics to GBS-colonized women during delivery.The aim of this study is to determine the prevalence of GBS colonization among pregnant women attending the outpatient clinic at department of obstetrics and gynecology in Tanta University Hospital. The study also aims to evaluate both of GBS antigen detection test and chromogenic media in comparison with conventional culture method as a two rapid screening methods for GBS colonization. |