الفهرس 
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Abstract
Type 1 diabetes mellitus represents a significant global health problem. The metabolism of several minerals has been reported to alter in diabetes mellitus and these elements might have specific roles in the pathogenesis and progress of this disease. Of these minerals magnesium is the important one.
Aim of the work:
The aim of the present study was to evaluate magnesium levels and examine their possible association with glycemic control in children with T1DM.
Subjects and methods:
The study was conducted upon 125 children who were grouped as follows.
group I: (Study group) This group included 75 children with proven diagnosis of diabetes mellitus type 1 and had regular follow up in pediatric endocrinology outpatient’s clinic at Minia University Hospital Children.
group II: (Control group) This group included 50 normal children age and sex matched with the previous group who were selected from outpatient clinic.
All patients were subjected to full history taking, clinical examination and laboratory investigations including:
- Serum magnesium, serum phosphorus, serum calcium, serum potassium, serum sodium and serum creatinine levels.
- Glycosylated Hb (HbA1c).
- Urinary microalbumin.
Samples were sent to clinical Pathology department at Minia University Hospital.
Results:
It was found that seum magnesium level was statistical significantly lower in diabetic group than control group.
Furthermore, our study revealed that there were a negative correlation between setrum magnesium and HbA1c as serum magnesium levels were significantly lower in the subgroup with poor glycemic control compared with the group with good glycemic control.
Moreover in our study we found a correlation between weight, BMI, duration of diabetes and HbA1c as in poorly controlled diabetics weight, BMI and duration of diabetes mellitus were significantly high when compaerd with good control diabetics.