الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Water-enema multidetector computed tomography (WE-MDCT) is a CT technique based on the distension of the colon using water. It provides excellent accuracy for the detection and localization of colon cancer.
Colonoscopy, the gold standard exploration for the rectum and colon, enables direct visualization of the entire colon; biopsies or resection of identified polyps can be performed as needed. Colonoscopy is recommended for populations with a high or very high risk of colorectal cancer.
The aim of this study is to evaluate the role of water enema CT Colonography versus colonoscopy in the diagnosis of colorectal carcinoma.
This study included 30 patients with clinically suspected colorectal carcinoma with mean age 52.93 +/- 14.54. 15 patients were males (50 %) and 15 patients were females
(50 %). The clinical presentation in majority of cases was bleeding per rectum (66.7 %) and colicky abdominal pain (30 %).
Thirty-one lesions were detected by WE-CTC and/or colonoscopy.
WE-CTC diagnosed 24 lesions as colorectal carcinoma correctly, 3 false positive lesions with high degrees of sensitivity of (88.89 %), positive predictive value (88.89 %), and accuracy (80.65 %). One true negative lesion and three false negative lesions with low degrees of specificity (25 %) and negative predictive value (25 %).
Colonoscopy diagnosed 22 lesions as colorectal carcinoma, 2 false positive lesions, 2 true negative lesions, and 5 false positive lesions. Colonoscopy yielded high sensitivity (81.48 %), positive predictive value (91.67 %), and accuracy (77.42 %). colonoscopy had low specificity (50 %) and negative predictive value (28.57 %).
This study included 26 patients with colorectal carcinoma, detected by WE-CTC and colonoscopy, and proven by biopsy. Another diagnosis other than colorectal carcinoma in four patients; One patient with diverticulitis, one patient with carcinoid tumor, one patient was considered metastatic disease from gastric adenocarcinoma, and one patient had anal obstructing lesion and no biopsy obtained from the suspicious sigmoid colon lesion detected on WE-CTC.
Since it is well known that Colonoscopy is the preferred diagnostic test for detecting colorectal cancers (CRCs), our study has shown that WE-CTC has better sensitivity and accuracy, and nearly similar positive predictive value.