الفهرس 
Anatomy and physiology of the prostate
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Abstract
Summary & Conclusion
Lower urinary tract symptoms(LUTS)due to BPH is a very
common condition among older men throughout the world
with approximately 25% of men over the age of 40 suffering
from (LUTS)that affect quality of life by interfering with
normal daily activities and sleep patterns.
Nocturia is a complaint that an individual wakes one or
more times to void urine at night due to urge . Nocturia may
be due to urological and non-urological diseases,The
common non urological conditions are excess fluid intake at
night or during the day , Other causes include diabetes
mellitus (DM), diabetes insipidus (Dl), congestive heart
failure (CHF), neurologic disorders, hypertension, sleep
disorders, and medications such as diuretics, cardiac
glycosides, phenytoin and calcium antagonists. The most
common urological conditions are benign prostatic
hyperplasia, Detrusor over activity, Neurogenic bladder,
Cystitis, Stones, Neoplasms é. prostate cancer , urinary
urgency, lower urinary tract surgery.
Most of the nocturia is considered as associated condition
and thus treated by medications for BPH or overactive
bladder (OAB) or such as with ablocker, 5a-reductas
inhibitor and antimuscarinics in daily practice.Unfortunately,
the response seems to be unsatisfactory. Desmopressin has
been proven to be an effective treatment for nocturia alone or
in combinations with other drugs as Alpha blockers for years
Desmopressin, a synthetic antidiuretic hormone analogue,
is currently approved for the treatment of nocturia along with
nocturnal polyuria. At present, the first-line medications fornocturia are desmopressin acetate and several different
antimuscarinic agents