الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
This cohort prospective hospital-based study was carried on 63
patients, aged 18 or above, who need ventilatory support in the ICU of our Department of Neuropsychiatry and center of neurology, psychiatry and neurosurgery, Tanta University Hospitals during a 12-month period started from May 2016. Patients already intubated and decided to be ventilated at the time of admission and whom who died before introduction of mechanical ventilation were excluded. The aim of the work is to assess clinical predictors and prognosis for the studied patients. The studied patients were categorized to 5 groups according to main cause of intubation and/or ventilation: ▪ group I: 7 patients intubated for airway protection or ventilated for suppression of epileptic activity with no respiratory failure. ▪ group II: 15 patients ventilated for central cause of respiratory failure ▪ group III: 21 patients ventilated for failure in respiratory mechanics secondary to the neurological insult (e.g. aspiration pneumonia, stunned myocardium, neurogenic pulmonary edema and pulmonary embolism) ▪ group IV: 14 patients ventilated for respiratory failure caused by peripheral nervous disorder. ▪ group V: 6 patients ventilated for causes unrelated to the neurological insult (e.g. COPD, acute renal failure, …). Studied patients were subjected to: ▪ History taking including the personal history and comorbid conditions ▪ Neurological and general clinical examination - 99 - ▪ Radiological studies according to each case included non-enhanced CT brain, MRI brain, chest imaging, nerve conduction studies, electromyography and echocardiography. ▪ Routine laboratory investigations including arterial blood gases, complete blood picture, prothrombin time and activity, international normalized ratio, liver & renal functions, lipid profile and further lab investigations were ordered for each case individually (e.g. D-Dimer, LDH, CSF analysis, … etc) ▪ Prognostic/outcome scores including ICU scores: APACHE-II and.