الفهرس 
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Abstract
Pruritus is a common symptom in chronic hemodialysis patients, with significant impact on quality of life. Despite improvements in dialytic technology, the incidence of uremic pruritus remains elevated in dialysis patients. A sharp increase in the prevalence of pruritis was observed in advanced chronic kidney disease (CKD) patients on dialysis.
Although the exact pathophysiologic mechanisms leading to pruritus in uremic patients are still under investigations, increased levels of vitamin A in these patients have been suggested as an etiological factor.
The present study is a descriptive cross-sectional study aimed to estimate the severity of pruritus in patients with advanced CKD andhemodialysis with serum vitamin A concentrations and also describes the differences in serum vitamin A in advanced CKD patients with and without pruritus in order to examine the proposed role of vitamin A in the pathogenesis of uremic pruritus.