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Abstract This study was conducted to investigate the effect of zinc oxide nanoparticles (ZONPs) on growth performance. A total of ninety-one-day old broiler chicks (ROSS 308) were on three dietary treatments (T) with three replicates in each treatment. T1; basal diet + 40 mg/kg inorganic ZnO, T2; basal diet + 40 mg/kg ZONPs, T3; basal diet + 80 mg/kg ZONPs. The results showed significant increase (p<0.05) in the body weight gain and improved feed conversion ratio in the groups fed 40 and 80 ZONP, but feed intake showed non-significant difference. The activity of (SOD) and Catalase were significantly increased however; (MDA) was significantly decreased in the same groups. Serum IgY also increased in the groups fed 80 ZONPs. Phagocytic activity and lymphocytic proliferation test showed significant increase with ZONPs fed groups. The villus height and crypt depth were significantly increased in all parts of the small intestine in the groups fed 80 ZONPs. So, it could be concluded that dietary supplementation of 40 or 80 mg ZONPs for broilers have beneficial effects on the growth performance, antioxidant status, immunity, absorptive mechanism of broiler chickens. Key words: Zinc oxide nanoparticles, Growth performance, Antioxidant status, Immunity status, Absorptive capacity, Broiler chickens. |