Search In this Thesis
   Search In this Thesis  
العنوان
The Role of Helicobacter Pylori in chronic Tonsillitis /
المؤلف
Abd El-Hadi, Omnia Abd Elaal.
هيئة الاعداد
باحث / أمنيه عبدالعال عبد الهادي
مشرف / أحمد محمود يوسف
مشرف / هبه محمد توفيق
مشرف / أحمد عبدالرحمن عبدالعزيز
الموضوع
Tonsils - Diseases. Tonsillitis.
تاريخ النشر
2017.
عدد الصفحات
97 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الحنجرة
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة المنيا - كلية الطب - الأنف والأذن والحنجرة
الفهرس
Only 14 pages are availabe for public view

from 110

from 110

Abstract

Chronic tonsillitis:Chronic tonsillitis is a common condition characterized by persistent inflammation of the palatine tonsils, and bacterial infection is usually the cause.
Idiopathic tonsillar hypertrophy presents without a history of infection and sometimes leads to obstructive sleep apnea and dysphagia.
Pharyngitis and tonsillitis are among the most common infections of the upper respiratory tract. There are many studies confirming the presence of Helicobacter pylori in the saliva, oral cavity.
Helicobacter pylori is the major gastric pathogen which has an important role in the etiopathogenesis of chronic gastritis.
Helicobacter pylorus (H. pylori) is a microaerophilic gram-negative comma shaped bacterium that colonizes the human stomach.
Its a worldwide bacterial infection that has prevalence of about 30%in developed and up to 90% in underdeveloped countries.
We investigated the presence of Helicobacter pylori as an extragastric reservoir in the tonsillectomy specimens to display if it is an etiologic factor in the development of chronic tonsillitis. This study is a prospective cross sectional analysis of 50 consecutive cases of patients undergoing tonsillectomy secondary to chronic recurrent tonsillitis was done,(23 male and 27 female) with age ranges from 3-15, with mean 5, 6±2.
These children underwent the following: Full E.N.T examination, systemic investigation, Rapid urease test for tonsillar tissues specimens. Detection of H.pylori antigen in stool, Histopathologic examination in the E.N.T. department of EL-Minia University hospital.
Rapid urease test was conducted on each tonsillectomy tissue and results were determined using color change at specific time intervals within 24 h.Among the 50 tonsillar tissues analyzed using rapid urease test, H. pylori was present in 56% of the samples. In the current study, statistically there was no significant difference by chi-square test between female and male who showed H.pylori. Rapid Urease Test was positive in 28(56%) negative in 22 (44%).The sensitivity of RUT was90%, specificity 73 %, PPV39, 9 % and NPV 88, 4 %.
Colonization by H. pylori of the palatine tonsils is a new frontier with conflicting results depending on the accuracy of the test method used and population studied.
More studies need to be performed to as certain the different rates of colonization based on geographical regions.
Clinical findings of histopathological examination: Out of 50 cases, the patient’s age range was between 3-15 of which 23were males (46%) and 27 were females (54%). H. pylori was identified clearly in the histopathologic evaluation of H&E sections, out of 50 cases, the microorganism H. pylori-like microorganisms was detected on in 29 of cases(58%). Statistical analysis revealed correlation between the identification of H. pylori and the rural residence, but no correlation between the identification of H. pylori and age and gender of the cases. H. pylori antigen in stool test, out of 50 cases, H.pylori antigen in stool was detected in 29 of cases (58%).