الفهرس 
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Abstract
The thesis includes two parts:
Part I: Synthesis and reactions of 4-(4-ethylphenyl) or/and 4-
(biphen-4-yl) phthalazine -1(2H)-one.
Reaction of 2-(4-ethylbenzoyl) and /or 2-(biphen-4-yl) benzoic
acid (1a-b) with hydrazine hydrate in boiling ethanol afforded
compounds (2a-b).
Reaction of compound (2a) with chloro acetyl chloride in pyridine
afforded compound (3).
Reaction of compound (2a) with Allyl bromide in dioxane afforded
compound (4).
Reaction of compound (2b) with chloro ethanol in ethanol afforded
compound (5).
Reaction of compound (5) with resorcinol, catechol, hydroquinone, 2-
hydroxy benzoic acid and pyrazine-1(4H)-carboxylic acid in boiling
ethanol afforded compounds (6a-e).
Reaction of compound (6b) with acetic anhydride in dry acetone
afforded compound (7).
Reaction of compound (2a) with phenyl isothiocyanate in benzene
afforded compound (8).
Summary
ii
Reaction of compound (2a) with morpholine, formaldehyde solution
38% and one DROP of HCl in ethanol afforded compound (9).
Reaction of compound (2a) with phosphorus pentasulfide in dry xylene
gave compound (10).
Reaction of compound (2a) with N-ethoxycarbonyl piperazine,
formaldehyde solution 38% and one DROP of HCl in ethanol afforded
compound (11).
Reaction of compound (2a) with ethyl chloroacetate in pyridine gave
compound (12).
Reaction of compound (2b) with chloro acetic acid in ethanol afforded
compound (13).
Reaction of compound (2b) with succinic acid in ethanol afforded
compound (14).
Reaction of compound (2a) with pyrazolidine-3,5-dione, aldehydes as
benzaldhyde, p-chlorobenzaldhyde and p-methoxybenzaldhyde, and
[simp]HSO4 in ethanol afforded compounds (15a-c).
Reaction of 2-(4-ethylbenzoyl) benzoic acid (1a) with thiocarbazide in
pyridine afforded compound (16)