الفهرس 
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Abstract
Lung cancer is the most commonly diagnosed cancer worldwide and its incidence continues to grow. Among all cancers, lung cancer now has the highest mortality rate in most countries (Ridge et al., 2013).
Determination of histopathological cell type and stage of primary lung carcinoma is crucial in immediate planning of appropriate treatment modality and prognosis (Porter et al., 2002).
Factors that affect the success of diagnostic modality are diameter and localization of the mass, and visibility at endobronchial tree with bronchoscope. The most prevalent diagnostic tool in central and exophytic endobronchial lesion is bronchoscopy (Rivera et al., 2003).
Bronchoscopy has become an essential tool for the respiratory physician. The modern fiberoptic video bronchoscopes provide high-definition images of the airways so that even subtle lesions are recognized (Grange et al., 2006).
The use of the cryotherapy probe allows sampling of endobronchial tumors, producing well-preserved tissue, which tends to be of superior quality to that obtained by flexible forceps biopsy (FB). Recent studies demonstrate that cryobiopsy (CB) samples are devoid of the crush artifact commonly seen in biopsies obtained with traditional forceps. CB also yields much larger samples than FB (Moeller et al., 2008).
Results revealed that the only detected complication during both procedures was bleeding. There was no significance in bleeding intensity between two groups. Therefore difference in haemostatic maneuver in both procedures was insignificant.
All patients in the study were males (n = 40) with mean age of 60.25 ± 6.48 that showed male predominance in relationship with BGC.
Regarding histopathological examination for tissue biopsies (n = 37), 94.5% were diagnosed non small cell lung cancer (NSCLC). 40.5% by FB and 54.0% by CB. Squamous cell carcinoma (SCC) 57.1%, Adenocarcinoma 42.8% and 5.5% were diagnosed as lung small cell carcinoma (SCLC) and both of them by FB.