الفهرس 
Introduction and RationaleOnly 14 pages are availabe for public view
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Abstract
Rheumatic fever and rheumatic heart disease continue to be a major health hazard in most developing countries as well as sporadically in developed economies .
Generally, LV systolic function is well preserved in pure MS, unless there is a coexisting MR . However, there are some studies pointing out impaired LV systolic function in pure MS.
Myocardial structural changes and hemodynamic factors may play a role in the impairment of LV systolic function. Extension of inflammation through adjacent myocardium may lead alterations in systolic functions . chronic decrease in preload and increase in afterload are also responsible for impaired LV systolic function in isolated MS .
Conventional parameters are not able to demonstrate subclinical LV dysfunction in MS patients. Tissue Doppler imaging (TDI) is a novel technique that has been shown to be reliable and accurate for evaluating global and regional ventricular functions.
The objective of this study is to assess prevalence of LV systolic dysfunction in patients with isolated rheumatic mitral stenosis with exclusion of other factors causing LV systolic dysfunction , as rheumatic myocarditis may be a cause for this condition , so we may identify subclinical systolic dysfunction in patients with isolated MS . These findings may provide us with good prognostic information and may