الفهرس 
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Abstract
Objective: The aim of this study was to link the circulating serum visfatin with women with gestational diabetes and normal pregnant females and its association with glycaemic control, insulin resistance and lipid profile.
Patients and Methods: Our study was conducted on 50 subjects, selected from the outpatient clinic of the Obstetrics and Gynaecology Department of Ain Shams University Hospital. They were divided into two groups. group 1 contained 30 women with gestational diabetes. group 2 contained 20 normal pregnant women.
All the enrolled subjects were conducted to full medical history taking, thorough clinical examination and laboratory investigations.
Results: The study has revealed a highly significant difference between the two study groups as regard fasting and 1 hour post prandial Visfatin with a higher mean among the Diabetic group. The study also showed a high positive correlation between BMI and Fasting Visfatin among all cases. There was similarly a highly significant positive correlation between BMI and 1 Hour post prandial Visfatin among all cases. The study showed a highly significant positive correlation between each of the fasting serum insulin, HOMA-IR, HBA1C and fasting visfatin among all cases.
Conclusion: The study showed a highly significant positive correlation between each of the fasting serum insulin, HOMA-IR, HBA1C and 1 hour post prandial visfatin among all cases. There was no statistical significant difference between the two study groups as regard systolic blood pressure, diastolic blood pressure, lipid profile, age, weeks of gestation and BMI in our conducted study. To conclude, there are a few explanations as to why the serum visfatin does rise in gestational diabetes mellitus.