الفهرس | Only 14 pages are availabe for public view |
Abstract Primary open angle glaucoma (POAG) is defined as an optic neuropathy of multifactorial origin whose main characteristic feature is optic nerve head (ONH) damage due to a loss of ganglion cells. Although the main known risk factor for disease onset and progression is elevated intraocular pressure (IOP), reports exist of a link between corneal properties, such as corneal thickness, and susceptibility to glaucoma. In effect, reduced central corneal thickness (CCT) is regarded as a risk factor for the development and progression of POAG. Many studies have reported that thinner corneas may lead to underestimated IOP, and for thicker corneas, IOP may be overestimated. However, the effect of CCT on IOP readings alone seems insufficient to explain the increased susceptibility to glaucoma detected in individuals with thinner cornea. In the Ocular Hypertension Treatment Study, a low CCT value was identified as a risk factor for conversion of patients with ocular hypertension to POAG, after statistical correction for IOP and other risk factors. A total of 60 eyes of 30 subjects fulfilled the inclusion criteria for the study. They were equally distributed between the study (n=15) and control (n=15). In addition to a routine ophthalmic examination, all eyes were examined with the pentacam (Oculus inc.Lynnwood,Washington) by the same examiner; the anterior and posterior elevation maps were analyzed in the central 7-mm diameter area. The elevation parameters recorded for the analysis were the maximum. |