الفهرس 
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Abstract
This study was done on 200 Nile tilapia (Oreochromis niloticus) of different ages were collected from farms of Central Laboratory for Aquaculture Research during period from late November, 2014 to march, 2016. The collected fish samples were clinically diseased, respiratory manifestation, ulcer and hemorrhages on body surface, cotton wool like lesion on skin, eye opacity and detached scale. The collected fish were suspected to post mortem and Mycological examination by different method. Eleven fungal isolates were identified, Saprolegnia spp., Asp. niger, Asp. flavus, Asp. ochraceus, Asp. terreus, Asp.versicolor, Zygomycets group, Penicillium spp., Fusarum spp., Cladosporium spp. and Candida albicans. The study revealed that Asp. niger was the most fungus isolated and affected fish during summer season, while Saprolegnia spp. was the most fungus affected fish and isolated during winter season . Saprolegnia spp. was responsible for high percentage of mortality among affected fish and also decreased percentage of hatchability among affecting fish eggs. This study discussed the high efficacy of Ruta Graveolens extract in prevention of growth of Saprolegnia spp. in vitro, also described the efficacy of iodine in controlling egg Saprolegniasis. Also this study revealed that raw garlic prevents growth of Asp. niger, Asp. flavus and Cladosporium spp. in vitro.
Key words: Aspergillus, Nile tilapia, species.