الفهرس 
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Abstract
ABSTRACT
Aim of the work: this study aimed to assess the clinical usefulness of the ADC calculated from DW MR images in the characterization of the head and neck masses in pediatrics. Patients and method: this study was carried out in the Radiology Departments of Ain Shams University Hospitals and the National Cancer Institute. A total of 60 patients presented with head and neck masses. They were 22(36.7%) females and 38 (63.3%) males. Their age was ranged from 3 days -18 year old. Results: The calculated ADC values of the lesions ranged from 0.15 – 3.70x 10-3 mm2/sec with mean of 1.12 ± 0.69. The difference between the ADC values of benign and malignant lesions was statistically significant with p value (p<0.001). The ADC value of benign and malignant lesions was 1.66 ± 0.59 x10-3mm2/sec and 0.64 ± 0.29 x10-3mm2/sec respectively. A cutoff value of ADC<1x10-3mm2/sec obtained from our study showed overall accuracy 96.7%, Sensitivity 96.9%, Specificity 96.4%, Positive predictive value (PPV) 96.9% and Negative predictive value (NPV) 96.4%. Conclusion: ADC value is considered as an essential non-invasive diagnostic tool for the characterization of the head and neck masses in pediatric age group. There is strong inverse relationship between the ADC value and possibility of being malignant, the lower ADC value the more possible to be malignant and vice versa , but one should put in consideration the degree of overlap between the ADC value of the malignant and benign lesions.
Keywords: DW MR, ADC, congenital