الفهرس 
Platelet AbnormalitiesOnly 14 pages are availabe for public view
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Abstract
Biological markers useful for defining patient with newly diagnosed pt immune thrombocytopenic purpura (ITP) who are likely to develop the chronic form of the disease are partially lacking. The purpose of this study was to assess the clinical role of cytokines in patient with ITP and correlate its levels with different disease stages.
20 patient with ITP at the onset of their disease, 40 chronic, and 30 healthy matched controls enrolled in this study. Serum levels of IL10 was measured in all patient using quantitative immunoenzymatic assays.
Serum IL10 levels were significantly higher in patients with an acute evolution of ITP than in either healthy controls or patients with chronic ITP.
Conclusion. IL-10 seems to predict the clinical course of ITP, as it is significantly higher at the onset of disease in patients who obtain disease remission in less than 1 year.