الفهرس | Only 14 pages are availabe for public view |
Abstract Abstract Background: Magnesium sulphate (MgSO4) has been used as an adjuvant in brachial plexus block with encouraging results; however, there is no consensus regarding its optimal dose. Thereby, we compared the efficacy of two doses of MgSO4 as an adjuvant in ultrasound guided (USG) supraclavicular brachial plexus block. Aim of the work: to compare the effects of adding either 200 or 600 mg of MgSO4 to bupivacaine in ultrasound-guided supraclavicular nerve block in upper limb surgeries. The comparison included the onset, the duration of the sensory and motor blocks, their effects on the postoperative pain scores, as well as the anticipated complications. Methods: Thirty patients belonging to American Society of Anesthesiologists physical status I, II or III, aged between 18 to 70 years old with ideal body weight 60-90 Kg undergoing upper limb surgeries with duration less than 2 hours, were enrolled. They were randomly divided into 2 equal groups. In group (I) patients received 200 mg MgSO4 (2 ml) + 12 ml of bupivacaine (0.5%) + 6 ml normal saline, while patients of group (II) received 600 mg of MgSO4 (6 ml) + 12 ml of bupivacaine (0.5%) + 2 ml normal saline. Ultrasound-guided supraclavicular nerve block technique was used in both groups. The onset and duration of the sensory and motor blocks were monitored and evaluated using the pinprick and modified Bromage scale. Assessment of the postoperative pain was done using numeric pain rating scale (NPRS). Results: there was no significant differences regarding the demographic data and the mean duration of surgery of the investigated patients of the two groups (P >0.05). The addition of 600 mg of MgSO4 to bupivacaine in ultrasound-guided supraclavicular nerve block significantly shortens the mean onset times of sensory and motor blocks and significantly prolongs their duration of action (P < 0.05) in comparison with 200 mg MgSO4 with no reported side effects. Conclusion: The present results indicated that the increase of MgSO4 dose up to 600 mg as an adjuvant added to bupivacaine in supraclavicular nerve block will give better effects. |