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Abstract Anemia is a common problem in critically ill patients and is associated with major morbidity and worse outcomes. Also, blood transfusion is a common practice in intensive care unit and has many complications. Information from critically ill patients suggests that lower mortality rates are associated with more conservative blood transfusion policy.This study was done to evaluate ScvO2 and oxygen extraction as suitable indicators for blood transfusion to decrease blood transfusion in intensive care unit.Mixed venous oxygen saturation sampled from the pulmonary artery is ideal for measurement of DO2 and VO2. However, because of the difficulty of obtaining SvO2 in critically ill patients, ScvO2 was suggested as alternative for SvO2.Central venous catheters(CVCs)are easier to insert, and typically safer and less expensive than PAC. The CVC allows sampling of blood for measurement of ScvO2. This study was approved by Ethical Committee and carried out in Tanta University Hospitals in surgical intensive care unit on forty anemic patients (Hb < 7g/dl). A written informed consent was obtained from all patients. The inclusion criteria of the patients in this study were patients with Hb < 7g/dl, aged above 18 years, with central venous pressure(CVP) from 8-12 cm H2O, mean arterial blood pressure (MAP) ≥ 65.mm Hg and urine output ≥ 0.5 ml/kg/hr The exclusion criteria were patients with increased oxygen consumption (shivering, epilepsy,pain),ongoing hemorrhage, sho of any origin and any patient on vasopressor support, chronic anemia,hypoxemia and patients with ischemic heart disease, acute coronary syndrome or heart failure. |