الفهرس 
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Abstract
This thesis aim to compare between both urinary 1)2- microglobulin (1)2-m ) and retinol binding
protein (RBP) in order to choose suitable marker of early tubular damage .Our study conducted on
twenty patients of renal tubular damage (11 male & 4female) .They were chosen among those
attending to Ain shams University Hospital
.Both groups of patients as well as the controls were subjected to detailed history taking and
laboratory investigation to estimate urinary 1)2-m and RBP .It was found that patients who suffered
from renal tubular damage had higher levels of both 1)2-m &RBP and they were significantly
correlated ;but in view of stability RBP appears to have greater stability at pH <5.5 . So we
conclude that RBP is a more practical and reliable index of renal tubules than !)2-m.
This thesis aim to compare between both urinary 1)2- microglobulin (1)2-m ) and retinol binding
protein (RBP) in order to choose suitable marker of early tubular damage .Our study conducted on
twenty patients of renal tubular damage (11 male & 4female) .They were chosen among those
attending to Ain shams University Hospital
.Both groups of patients as well as the controls were subjected to detailed history taking and
laboratory investigation to estimate urinary 1)2-m and RBP .It was found that patients who suffered
from renal tubular damage had higher levels of both 1)2-m &RBP and they were significantly
correlated ;but in view of stability RBP appears to have greater stability at pH <5.5 . So we
conclude that RBP is a more practical and reliable index of renal tubules than !)2-m.