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Abstract ABSTRACT Background: Anemia is the most frequent disturbance of physiology in the world throughout the life of a woman. It is a serious condition in the developing countries and also in the developed countries resources. Most common causes of anemia are malnutrition, iron deficiency, folic acid deficiency, vitamin A deficiency and vitamin B12, deficiency diseases like malaria, hookworm infestation and schistosomiasis, HIV infection and genetically inherited hemoglobinopathies such as thalassemia. Maternal anemia is frequently associated with preterm labor, neonatal low birth weight, infant iron deficiency, neonatal death, and low Apgar scores at 1 min. It is also suspected to reduce the oxygen supply to the growing fetus, leading to the redistribution of fetal blood flow. Aim of the Work: This study aims to assess the changes in fetal cerebral and Umbilical artery resistance index in women with severe iron deficiency anemia using non invasive measurement (colour Doppler ultrasound). Patients and Methods: This is a prospective case-control study which included 100 pregnant women who attended at Ain Shams University Hospitals Obstetrics Outpatient Clinic and Casualty Department, in the period from January 2017 to October 2017. These pregnant ladies were divided in to two groups (each group included 50 subjects): group A: anemic group (with Hb levels ≤ 7 gm/dL), group B: control group (with Hb levels ≥ 11gm/dL). Results: The following tables and graphs will show the comparison between both groups under the study: (A) anemic group and (B) control group. Conclusion: This study showed that severe IDA had affected both pregnancy and delivery outcome. Fetal MCA Doppler RI of the Anemic group was significant lesser than control group (0.70 vs. 0.77). The RI ratio between MCA and UA in the Anemic group was highly significant worse than the Control group (0.92 vs 1.098). |