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العنوان
Single Nucleotide Polymorphism in the MTHFR Gene and Its Relation to Hypertension in Obese Children/
المؤلف
El dabdob,Mohammed Saad Mohammed
هيئة الاعداد
باحث / محمد سعد محمد الدبدوب
مشرف / وسام أحمد إبراهيم أحمد
مشرف / آلاء يوسف أحمد
مشرف / وسام أحمد إبراهيم أحمد
تاريخ النشر
2018
عدد الصفحات
147.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2018
مكان الإجازة
جامعة عين شمس - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

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Abstract

Our study revealed a highly statistically significant positive correlation between hypertension and MTHFR gene SNP.
Regarding the C667T polymorphism, a higher frequency was detected among obese hypertensive children (60%) than obese normotensive children (26.7%) with a highly significant difference between them (p =0.009).
Genotypic analysis of the cases regarding C667T MTHFR revealed that 25 patients (35.7%) had genotype (CC), While 45 patients (64.3%) had mutant type, and 42 of them (60%) were heterozygous genotype (CT) and 3 (4.3%) were homozygous genotype (TT