الفهرس 
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Abstract
Foot and Mouth Disease (FMD) is a highly contagious
vesicular virus disease of buffaloes, cattle, sheep, goats, wild
ungulates (giraffe and deer), as well as pigs and other clovenhoofed
wild and domestic mammals
The present study was conducted on forty five native breed
Egyptian cattle (female non pregnant) aged 1-5 years. These cattle
were belonging to different localities in port- Said Governorate
(Bahr El-Baker, El kabboti El Gadid, El Radwan, El Asher and Sahl
Tena) in Egypt during FMD outbreak (2016-2017).
The animals were divided into two main groups.
group (1): 15 apparently healthy cattle considered as control group.
This group subdivided into: (gp.1a): animals at age 1-
1.5 year, (gp.1b): 2-3 years and (gp.1c): 4-5 years.
group (2): 30 cattle manifested the characteristic clinical signs of
FMDV infection. This group subdivided into: (gp.2a):
animals at age 1-1.5 year, (gp.2b): 2-3 years and
(gp.2c): 4-5 years, 10 animals in each.
Two venous blood samples were collected from jugular vein of
cattle. The 1st sample (about 2 ml) of blood was taken in sterile
vacuum tube (with dipotassium salt of EDTA) used for
hematological studies. The 2nd sample (about 10ml) was taken in
sterile vacuum plain tube without anticoagulant for serum
separation for biochemical, serological and oxidative profiles.
Samples for molecular biology study (PCR): Tongue
epithelium and vesicular fluid were collected in sterile tube (with
glycerol saline) for virus isolation for PCR.