الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 129 |  |  |
| | | from | 129 | | |
Abstract
Vitiligo is an acquired depigmented skin disorder caused by loss of functioning MCs characterized by milky white patches anywhere on the body.
Available methods for treatment of vitiligo are medical, physical and surgical. Surgical treatment is an option for repigmentation in patients with stable vitiligo that are refractory or partial responsive to medical treatment. Different surgical techniques are based on common principle which transplant autologous MCs from normal pigment donor skin to depigmented area. Of these techniques, punch grafting is considered an easy and safe method which can be done in the outpatient clinics.
The aim of this work was to compare between 1mm and 1.5 mm punch grafting in SV and NSV regarding the number of graft loss, the percentage of pigmentation, the degree of pigmentation between punches and for the development of cobblestoning
The present study was conducted on 36 vitiligo patients divided into 2 groups:
group 1 (20 patients with stable NSV) and group 2 (16 patients with stable SV): 1 mm and 1.5 mm punch grafting was done in both groups.
Remarkable repigmentation in the area between punches occurred with a statistically higher incidence of pigmentation after 1 mm than 1.5 mm punch graft both subjectively and objectively (p=0.026) (p=0.023) respectively.
As regard cobblestoning, in the present work we reported a statistically significant lower incidence of cobblestoning after 1 mm punch grafting than 1.5 mm punch grafting (p=0.009).
In conclusion, the use of smaller sized punch yields better results in terms of pigmentation. Moreover, the smaller diameter punch is more preferable decrease incidence of cobblestoning.