الفهرس 
Physiology of HemostasisOnly 14 pages are availabe for public view
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Abstract
Severe sepsis accounts for approximately 2.9% of admissions to hospital, 10% of admissions to the intensive care unit, and is the tenth leading cause of death in the intensive care unite (ICU), despite several decades of intense therapeutic investigation, the mortality remains up to 50%.
Severe sepsis is a common life-threatening condition in which an infectious agent triggers a series of pro-inflammatory reactions that manifest as hemodynamic imbalance, organ dysfunction and almost universal signs of coagulation abnormalities.
Aims: The aim of this essay is to throw light on the recent advances in sepsis-induced disseminated intravascular coagulation regarding pathophysiology and management.
Summary: Blood coagulation is essential to our health; however, when it proceeds abnormally, myocardial infarction, stroke, or pulmonary embolism can result. Maintaining blood in a fluid state is vital in order to deliver oxygen, nutrients, and physiological messengers throughout the body. The hemostatic system achieves this balance between the fluid and solid states of blood.
Conclusion: The treatment for DIC centers on addressing the underlying disorder, which ultimately led to this condition. Consequently, therapies such as antibiotics for severe sepsis represent the mainstays of treatment for DIC.