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Abstract Summary and Conclusion Intrauterine growth restriction (IUGR) is a major cause of perinatal mortality and morbidity. It is noted to affect approximately 5-15 % of pregnant women. Egypt has one of the highest incidences of IUGR. The incidence of Intrauterine Growth Restriction (IUGR) varies among countries, populations, races and increases with decreasing gestational age. 14 to 20 million infants have been affected with IUGR cases in the developing countries annually. IUGR may be symmetrical, in which all internal organs are reduced in size, or asymmetrical, in which the brain is normal in size but other organs are reduced in size. When growth restriction occurs in the first and early second trimester it tends to be symmetrical, but if occurs later in pregnancy it will be asymmetrical. A complex and dynamic interaction of maternal, placental and fetal environment is involved in ensuring normal fetal growth. An imbalance or lack of coordination in this complex system may lead to IUGR. The IUGR infant is at risk to develop an intrapartum fetal distress, hypoglycemia, hypothermia, meconium aspiration, impaired neurological development, necrotizing enterocolitis and intrauterine fetal death. Babies and intrauterine growth restriction (IUGR) have a wide range of perinatal complications, distinctive hematological abnormalities including polycythemia, thrombocytopenia and |